Thursday, November 29, 2012

Arizona declines to set up state-based health insurance exchange

PHOENIX (Reuters) - Arizona Governor Jan Brewer, an ardent critic of President Barack Obama's push to overhaul the U.S. healthcare system, said on Wednesday she was rejecting a new federal mandate to establish a state-based health insurance exchange under the U.S. Affordable Care Act.

Citing lingering unanswered questions about the exchanges and concerns about high costs she said would be passed on to Arizona families and small businesses, Brewer, a Republican, said her state would opt instead for a federally run exchange.

Such networks, designed to function as online insurance markets where consumers can shop for private coverage at federally subsidized rates, are an integral provision of the act, a centerpiece of Obama's first term in office.

(Reporting by David Schwartz; Writing by Steve Gorman; Editing by Cynthia Johnston)

Source: http://news.yahoo.com/arizona-declines-set-state-based-health-insurance-exchange-220349649.html

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Wednesday, November 28, 2012

Google adds detailed mapping to 45 Russian cities

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Were Yakov Smirnoff here, he'd probably try and crowbar in an "In Soviet Russia, cities Google you!" gag, but we're above such mischief. As such, we'll just let you know that Mountain View's Russian branch has added detailed mapping information for 45 new cities, including Vladivostok, Donetsk and Sochi, the home of the 2014 Winter Games. We'd suggest downloading the mapping data for the whole bunch while over your 3G connection and see if you don't win a prize, after all, it's happened before.

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Source: Google Russia (Translated)

Source: http://www.engadget.com/2012/11/27/google-maps-russia-45/

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Tuesday, November 27, 2012

Role Of SCUBA Diving Gear In Technical And Recreational Diving ...

If you had to ditch your gear would you be able to remove your BCD on your own? The bubbles that can be seen falling towards the divers? feet because are actually really rising to the surface. Scuba divers dive in shark cages and in most cases diving equipment rental tends to be cheaper than they would if you were not using a cage. For the past 25 years, the island of Phuket has catered for a large number of tourists from all over the world, a large percentage of whom are scuba divers looking to dive on some Asia?s finest dive sites. Orcas Island, the largest island off the coast of Washington state, is often called as ?gem of the San Juan islands?.

Look for a simple scuba workout combined with nearly any form of cardio to help you move into the ?fat but fit? category. It is not uncommon for a shark?s pectoral fin to glide just into the gap in the cage as it swims past. Louis club frequently gives back to its community in special ways. Keen surfers who are holidaying on the east coast should head over to Arugam Bay, widely renowned as one of the best surf spots in Sri Lanka. This means that the decision between renting your scuba gear and purchasing your scuba gear is even more critical if you?re above average in size.

If you don?t have a set of weights and a workout bench, get one. Even if you aren?t a diver, glass bottomed boat tours are offered here, and the beach is also noted as having some of the most active night life on the island. Therefore, you should also follow proper procedures before you take you nude diving adventure. Oxygen tanks and the tubes and mouthpieces which allow the user to inhale and exhale air from them are very common these days. This zero gravity environment provides the backdrop for romance, intrigue and adventure.

We often have rebreather divers joining us for some leisure diving or rebreather training in Kota Kinabalu, Sabah, Borneo and one of the questions we often get asked by recreational divers is ?How does a rebreather work??. Why Altitude Corrections for scuba diving? If you are already qualified either with BSAC or another recognised dive agency and looking to join a club, or returning after a break from the sport, then the club will be happy to welcome you with a discounted joining fee. The schools offer training to the individuals followed by the certificates. Artificial reefs are fantastic underwater attractions for divers and they also provide new habitats for underwater species.

They just made it an official PADI basic open water certification along with a membership to the club. In this case it would be best not to fret too much about your weight initially, instead concentrate on improving your overall fitness as it will have a much larger impact on your ability to scuba dive. Children and adults can learn about the ocean and all the animals found in it, up close and personal. Many divers risk their lives by overlooking certain risks. The oceans are full of things that humans can use to help with real life situations.

For deeper dives the Air Diluent would swapped out for different mixtures of Trimix (Helium, Nitrogen and Oxygen). The first requirement is the divers must be 10 years old to enroll in a diving course. If the outside pressure is 30 and inside pressure is 10, then eardrum will bulge inside, until the inside pressure is 30. One thing all of these events had in common is they were organized and planned especially for members in the pursuit of fun. In addition to the great feeling that you get while diving nude, there are also the safety considerations.

You have to remain calm while your face is being submerged in water, which can cause a natural reflex of feeling like you are going to drown. It is one of the most beautiful places on earth and only a few fortunate people take time to see the beauty that it has to offer. Cuba has the second largest barrier reef system in the world which sits in clear warm waters. Scuba diving is not only a fun activity for all but it can be useful in the field of marine biology. Dives of different depths are planned depending upon the experience of the divers.

You have to use more air than when you are younger and carrying the heavy equipment can be a bit of a problem. Cardiovascular fitness should be the area to focus your efforts as this will have the greatest effect on air consumption and general comfort while scuba diving. On 20th November, 1619, a hurricane hit the Caribbean island and the moorings gave way sending it crashing into the surrounding reefs and rocks. Travellers flock to the Indian Ocean destination for its warm turquoise crystal clear waters, pristine white sand and palm-infringed beaches, and luxury Maldives hotels comprising beach resorts and luxury water villas on stilts above the calm sparkling ocean waters. The area is well known for its beautiful colourful coral reefs and hundreds of species of tropical fish.

That?s not bad of an investment for the end results. If you feel that you are fit, even though you are considered to be overweight, then it is most likely that you will have little difficulty scuba diving, with the exception of possible equipment issues related to your size. It involves working of all muscle groups thus providing a complete cardiovascular exercise. ?In all of Ecuador there were 1,489 diver certifications issued in 2011. To organise a refresher course or a free taster session email or call the centre on 07951 855725 or trydives@bracknellscuba.org.uk.

We did most of our training in the locks at the submarine base. Dives of different depths are planned depending upon the experience of the divers.
scuba

Source: http://freebookfor.com/2012/11/24/role-of-scuba-diving-gear-in-technical-and-recreational-diving/

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Source: http://stantonmarsh88.typepad.com/blog/2012/11/role-of-scuba-diving-gear-in-technical-and-recreational-diving.html

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Friday, November 23, 2012

Protein folding: Look back on scientific advances made as result of 50-year old puzzle

ScienceDaily (Nov. 22, 2012) ? Fifty years after scientists first posed a question about protein folding, the search for answers has led to the creation of a full-fledged field of research that led to major advances in supercomputers, new materials and drug discovery, and shaped our understanding of the basic processes of life, including so-called "protein-folding diseases" such as Alzheimer's, Parkinson's and type II diabetes.

In an article in Science, Stony Brook University researchers reviewed the progress on a 50-year-old puzzle called the Protein Folding Problem. Ken Dill and Justin MacCallum of Stony Brook's Louis and Beatrice Laufer Center for Physical and Quantitative Biology show how a community of scientific researchers rose to tackle a grand-challenge problem of very basic science that had no obvious payoff at the time.

"Protein folding is a quintessential basic science. There has been no specific commercial target, yet the collateral payoffs have been broad and deep," the researchers said in their paper, The Protein Folding Problem, 50 Years On.

"We have learned that proteins fold rapidly because random thermal motions cause conformational changes leading energetically downhill toward the native structure, a principle that is captured in funnel-shaped energy landscapes. And thanks in part to the large Protein Data Bank of known structures, predicting protein structures is now far more successful than was thought possible in the early days. What began as three questions of basic science one half-century ago has now grown into the full-fledged research field of protein physical science."

This year marks the 50th anniversary of the 1962 Nobel Prize in Chemistry awarded to Max Perutz and John Kendrew for their pioneering work in determining the structure of globular proteins. That work laid the foundation for structural biology, which interprets molecular level biological mechanisms in terms of the structures of proteins and other biomolecules. Their work also raised the question of how protein structures are explained by physical principles.

Since Perutz and Kendrew discovered the structures of two proteins, nearly 80,000 protein structures have been discovered. The protein folding "problem" arose when Perutz and Kendrew were unable to make sense of how the folded structure of the protein molecule was related to its sequence of bead types. Ever since then, there has been great interest in understanding the protein-folding "code": how does a given string of amino acids lead to a particular balled-up ("native") structure of a protein?

Proteins are molecules that perform the basic functions in biological cells -- converting food to growth, to repairing DNA molecules and damaged cell parts, to motion in muscles, to transduction of signals in the brain and light in the eye, for example. Humans have about 20,000 different types of protein molecules. Each performs a different function. The abilities of proteins to perform such a broad array of powerful chemical functions arise from a peculiar principle of chemical structure and function, namely the folding of each protein. A protein is miniature string of beads, like a pearl necklace, where the bead-like component pieces are called amino acids. Amino acids come in 20 different types. The folding principle is that different sequences of amino acids strung together cause different protein molecules to ball-up in very specific, but different, ways, giving rise to their very different functionalities.

The protein folding problem became a set of three inter-related puzzles: What is the folding code? How does the protein find its one native structure in fractions of a second inside the cell (the needle-in-a-haystack problem)? And: Can we make a computer method that can discover new structures of proteins from the large number of amino acid sequences that are now known?

Dill, Director of the Laufer Center and Distinguished Professor of Physics and Chemistry, and MacCallum, a junior fellow at the Laufer Center, describe how huge advances have been made on all three fronts. They detail some very important collateral payoffs of this work that was completely unanticipated at the time, including the development of the IBM Blue Gene computer and distributed-grid computing, computer-based methods for discovering new pharmaceuticals, a deeper understanding of molecular mechanisms in biology, a deeper understanding of the inter-atomic interactions inside proteins (that has also involved Stony Brook Laufer Center researchers Carlos Simmerling, David Green, and Rob Rizzo), and a new class of very promising polymer materials called "foldamers."

Dill and MacCallum argue that what started out as one compelling question of basic science has now become an entire field of theoretical and experimental approaches in which many questions are now leading to a few answers and many more questions.

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Journal Reference:

  1. K. A. Dill, J. L. MacCallum. The Protein-Folding Problem, 50 Years On. Science, 2012; 338 (6110): 1042 DOI: 10.1126/science.1219021

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Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/~3/-AO1KPe6jy8/121122152910.htm

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ScienceDaily: Gene News

ScienceDaily: Gene Newshttp://www.sciencedaily.com/news/health_medicine/genes/ Genes and Genetics News. Read today's medical research in genetics including what can damage genes, what can protect them, and more.en-usThu, 22 Nov 2012 17:24:20 ESTThu, 22 Nov 2012 17:24:20 EST60ScienceDaily: Gene Newshttp://www.sciencedaily.com/images/logosmall.gifhttp://www.sciencedaily.com/news/health_medicine/genes/ For more science articles, visit ScienceDaily.Scientists describe elusive replication machinery of flu viruseshttp://www.sciencedaily.com/releases/2012/11/121122152928.htm Scientists have made a major advance in understanding how flu viruses replicate within infected cells. The researchers used cutting-edge molecular biology and electron-microscopy techniques to ?see? one of influenza?s essential protein complexes in unprecedented detail. The images generated in the study show flu virus proteins in the act of self-replication, highlighting the virus?s vulnerabilities that are sure to be of interest to drug developers.Thu, 22 Nov 2012 15:29:29 ESThttp://www.sciencedaily.com/releases/2012/11/121122152928.htmProtein folding: Look back on scientific advances made as result of 50-year old puzzlehttp://www.sciencedaily.com/releases/2012/11/121122152910.htm Fifty years after scientists first posed a question about protein folding, the search for answers has led to the creation of a full-fledged field of research that led to major advances in supercomputers, new materials and drug discovery, and shaped our understanding of the basic processes of life, including so-called "protein-folding diseases" such as Alzheimer's, Parkinson's and type II diabetes.Thu, 22 Nov 2012 15:29:29 ESThttp://www.sciencedaily.com/releases/2012/11/121122152910.htmStep forward in regenerating and repairing damaged nerve cellshttp://www.sciencedaily.com/releases/2012/11/121121145638.htm Researchers recently uncovered a nerve cell's internal clock, used during embryonic development. This breakthrough could lead to the development of new tools to repair and regenerate nerve cells following injuries to the central nervous system.Wed, 21 Nov 2012 14:56:56 ESThttp://www.sciencedaily.com/releases/2012/11/121121145638.htmArchitecture of rod sensory cilium disrupted by mutationhttp://www.sciencedaily.com/releases/2012/11/121121145621.htm Using a new technique called cryo-electron tomography, scientists have created a three-dimensional map that gives a better understanding of how the architecture of the rod sensory cilium (part of one type of photoreceptor in the eye) is changed by genetic mutation and how that affects its ability to transport proteins as part of the light-sensing process.Wed, 21 Nov 2012 14:56:56 ESThttp://www.sciencedaily.com/releases/2012/11/121121145621.htmAging: Scientists further unravel telomere biologyhttp://www.sciencedaily.com/releases/2012/11/121121130933.htm Researchers have resolved the structure of that allows a telomere-related protein, Cdc13, to form dimers in yeast. Mutations in this region of Cdc13 put the kibosh on the ability of telomerase and other proteins to maintain telomeres.Wed, 21 Nov 2012 13:09:09 ESThttp://www.sciencedaily.com/releases/2012/11/121121130933.htmNovel mechanism through which normal stromal cells become cancer-promoting stromal cells identifiedhttp://www.sciencedaily.com/releases/2012/11/121121104401.htm New understanding of molecular changes that convert harmless cells surrounding ovarian cancer cells into cells that promote tumor growth and metastasis provides potential new therapeutic targets for this deadly disease, according to new research.Wed, 21 Nov 2012 10:44:44 ESThttp://www.sciencedaily.com/releases/2012/11/121121104401.htmEvolution of human intellect: Human-specific regulation of neuronal geneshttp://www.sciencedaily.com/releases/2012/11/121120194926.htm A new study has identified hundreds of small regions of the genome that appear to be uniquely regulated in human neurons. These regulatory differences distinguish us from other primates, including monkeys and apes, and as neurons are at the core of our unique cognitive abilities, these features may ultimately hold the key to our intellectual prowess (and also to our potential vulnerability to a wide range of 'human-specific' diseases from autism to Alzheimer's).Tue, 20 Nov 2012 19:49:49 ESThttp://www.sciencedaily.com/releases/2012/11/121120194926.htmRibosome regulates viral protein synthesis, revealing potential therapeutic targethttp://www.sciencedaily.com/releases/2012/11/121120132906.htm Rather than target RNA viruses directly, aiming at the host cells they invade could hold promise, but any such strategy would have to be harmless to the host. Now, a surprising discovery made in ribosomes may point the way to fighting fatal viral infections such as rabies.Tue, 20 Nov 2012 13:29:29 ESThttp://www.sciencedaily.com/releases/2012/11/121120132906.htmHow does antibiotic resistance spread? Scientists find answers in the nosehttp://www.sciencedaily.com/releases/2012/11/121120121835.htm Microbiologists studying bacterial colonization in mice have discovered how the very rapid and efficient spread of antibiotic resistance works in the respiratory pathogen, Streptococcus pneumoniae (also known as the pneumococcus). The team found that resistance stems from the transfer of DNA between bacterial strains in biofilms in the nasopharynx, the area just behind the nose.Tue, 20 Nov 2012 12:18:18 ESThttp://www.sciencedaily.com/releases/2012/11/121120121835.htmScientists identify inhibitor of myelin formation in central nervous systemhttp://www.sciencedaily.com/releases/2012/11/121120100155.htm Scientists have discovered another molecule that plays an important role in regulating myelin formation in the central nervous system. Myelin promotes the conduction of nerve cell impulses by forming a sheath around their projections, the so-called axons, at specific locations -- acting like the plastic insulation around a power cord.Tue, 20 Nov 2012 10:01:01 ESThttp://www.sciencedaily.com/releases/2012/11/121120100155.htmTelomere lengths predict life expectancy in the wild, research showshttp://www.sciencedaily.com/releases/2012/11/121119213144.htm Researchers have found that biological age and life expectancy can be predicted by measuring an individual's DNA. They studied the length of chromosome caps -- known as telomeres -- in a 320-strong wild population of Seychelles Warblers on a small isolated island.Mon, 19 Nov 2012 21:31:31 ESThttp://www.sciencedaily.com/releases/2012/11/121119213144.htmCancer: Some cells don't know when to stophttp://www.sciencedaily.com/releases/2012/11/121119171403.htm Certain mutated cells keep trying to replicate their DNA -- with disastrous results -- even after medications rob them of the raw materials to do so, according to new research.Mon, 19 Nov 2012 17:14:14 ESThttp://www.sciencedaily.com/releases/2012/11/121119171403.htmMultiple sclerosis ?immune exchange? between brain and blood is uncoveredhttp://www.sciencedaily.com/releases/2012/11/121119163301.htm DNA sequences obtained from a handful of patients with multiple sclerosis have revealed the existence of an ?immune exchange? that allows the disease-causing cells to move in and out of the brain.Mon, 19 Nov 2012 16:33:33 ESThttp://www.sciencedaily.com/releases/2012/11/121119163301.htm3-D light switch for the brain: Device may help treat Parkinson's, epilepsy; aid understanding of consciousnesshttp://www.sciencedaily.com/releases/2012/11/121119114249.htm A new tool for neuroscientists delivers a thousand pinpricks of light to individual neurons in the brain. The new 3-D "light switch", created by biologists and engineers, could one day be used as a neural prosthesis that could treat conditions such as Parkinson's and epilepsy by using gene therapy to turn individual brain cells on and off with light.Mon, 19 Nov 2012 11:42:42 ESThttp://www.sciencedaily.com/releases/2012/11/121119114249.htmBlood cancer gene BCL6 identified as a key factor for differentiation of nerve cells of cerebral cortexhttp://www.sciencedaily.com/releases/2012/11/121119093848.htm The cerebral cortex is the most complex structure in our brain and the seat of consciousness, emotion, motor control and language. In order to fulfill these functions, it is composed of a diverse array of nerve cells, called cortical neurons, which are affected by many neurological and neuropsychiatric diseases. Researchers have opened new perspectives on brain development and stem cell neurobiology by discovering a gene called BCL6 as a key factor in the generation of cortical neurons during embryonic brain development.Mon, 19 Nov 2012 09:38:38 ESThttp://www.sciencedaily.com/releases/2012/11/121119093848.htmMinority report: Insight into subtle genomic differences among our own cellshttp://www.sciencedaily.com/releases/2012/11/121118141530.htm Scientists have demonstrated that induced pluripotent stem cells -- the embryonic-stem-cell look-alikes whose discovery a few years ago won this year's Nobel Prize in medicine -- are not as genetically unstable as was thought.Sun, 18 Nov 2012 14:15:15 ESThttp://www.sciencedaily.com/releases/2012/11/121118141530.htmSkin cells reveal DNA's genetic mosaichttp://www.sciencedaily.com/releases/2012/11/121118141524.htm The prevailing wisdom has been that every cell in the body contains identical DNA. However, a new study of stem cells derived from the skin has found that genetic variations are widespread in the body's tissues, a finding with profound implications for genetic screening.Sun, 18 Nov 2012 14:15:15 ESThttp://www.sciencedaily.com/releases/2012/11/121118141524.htmLikely basis of birth defect causing premature skull closure in infants identifiedhttp://www.sciencedaily.com/releases/2012/11/121118141432.htm Geneticists, pediatricians, surgeons and epidemiologists have identified two areas of the human genome associated with the most common form of non-syndromic craniosynostosis premature closure of the bony plates of the skull.Sun, 18 Nov 2012 14:14:14 ESThttp://www.sciencedaily.com/releases/2012/11/121118141432.htmDNA packaging discovery reveals principles by which CRC mutations may cause cancerhttp://www.sciencedaily.com/releases/2012/11/121117184658.htm A new discovery concerning a fundamental understanding about how DNA works will produce a "180-degree change in focus" for researchers who study how gene packaging regulates gene activity, including genes that cause cancer and other diseases.Sat, 17 Nov 2012 18:46:46 ESThttp://www.sciencedaily.com/releases/2012/11/121117184658.htmHepatitis C treatment's side effects can now be studied in the labhttp://www.sciencedaily.com/releases/2012/11/121116161059.htm Adverse side effects of certain hepatitis C medications can now be replicated in the lab, thanks to a research team. The new method aids understanding of recent failures of hepatitis C antiviral drugs in some patients, and could help to identify medications that eliminate adverse effects. The findings may aid the development of safer and more effective treatments for hepatitis C and other pathogens such as SARS and West Nile virus.Fri, 16 Nov 2012 16:10:10 ESThttp://www.sciencedaily.com/releases/2012/11/121116161059.htmReconsidering cancer's bad guyhttp://www.sciencedaily.com/releases/2012/11/121116124644.htm Researchers have found that a protein, known for causing cancer cells to spread around the body, is also one of the molecules that trigger repair processes in the brain.Fri, 16 Nov 2012 12:46:46 ESThttp://www.sciencedaily.com/releases/2012/11/121116124644.htmGene distinguishes early birds from night owls and helps predict time of deathhttp://www.sciencedaily.com/releases/2012/11/121116124551.htm New research shows that a gene is responsible for a person's tendency to be an early riser or night owl -- and helps determine the time of day a person is most likely to die.Fri, 16 Nov 2012 12:45:45 ESThttp://www.sciencedaily.com/releases/2012/11/121116124551.htmClues to cause of kids' brain tumorshttp://www.sciencedaily.com/releases/2012/11/121116091226.htm Insights from a genetic condition that causes brain cancer are helping scientists better understand the most common type of brain tumor in children.Fri, 16 Nov 2012 09:12:12 ESThttp://www.sciencedaily.com/releases/2012/11/121116091226.htmArthritis study reveals why gender bias is all in the geneshttp://www.sciencedaily.com/releases/2012/11/121115210541.htm Researchers have pieced together new genetic clues to the arthritis puzzle in a study that brings potential treatments closer to reality and could also provide insights into why more women than men succumb to the disabling condition.Thu, 15 Nov 2012 21:05:05 ESThttp://www.sciencedaily.com/releases/2012/11/121115210541.htmClass of RNA molecules protects germ cells from damagehttp://www.sciencedaily.com/releases/2012/11/121115172255.htm Passing one's genes on to the next generation is a mark of evolutionary success. So it makes sense that the body would work to ensure that the genes the next generation inherits are exact replicas of the originals. Biologists have now identified one way the body does exactly that.Thu, 15 Nov 2012 17:22:22 ESThttp://www.sciencedaily.com/releases/2012/11/121115172255.htmQuick test speeds search for Alzheimer's drugs: Compound restores motor function and longevity to fruit flieshttp://www.sciencedaily.com/releases/2012/11/121115152655.htm Researchers report that an efficient, high-volume technique for testing potential drug treatments for Alzheimer's disease uncovered an organic compound that restored motor function and longevity to fruit flies with the disease.Thu, 15 Nov 2012 15:26:26 ESThttp://www.sciencedaily.com/releases/2012/11/121115152655.htmProtein-making machinery can switch gears with a small structural change process; Implications for immunity and cancer therapyhttp://www.sciencedaily.com/releases/2012/11/121115133414.htm For the past several years, research has focused on the intricate actions of an ancient family of catalytic enzymes that play a key role in translation, the process of producing proteins. In a new study, scientists have shown that this enzyme can actually also work in another fundamental process in humans.Thu, 15 Nov 2012 13:34:34 ESThttp://www.sciencedaily.com/releases/2012/11/121115133414.htmPlant derivative, tanshinones, protects against sepsis, study suggestshttp://www.sciencedaily.com/releases/2012/11/121115133312.htm Researchers have discovered that tanshinones, which come from the plant Danshen and are highly valued in Chinese traditional medicine, protect against the life-threatening condition sepsis.Thu, 15 Nov 2012 13:33:33 ESThttp://www.sciencedaily.com/releases/2012/11/121115133312.htmStructure of enzyme topoisomerase II alpha unravelled providing basis for more accurate design of chemotherapeutic drugshttp://www.sciencedaily.com/releases/2012/11/121115132903.htm Medical researchers have for the first time described the structure of the active site core of topoisomerase II alpha, an important target for anti-cancer drugs. The type II topoisomerases are important enzymes that are involved in maintaining the structure of DNA and chromosome segregation during both replication and transcription of DNA. One of these enzymes, topoisomerase II alpha, is involved in the replication of DNA and cell proliferation, and is highly expressed in rapidly dividing cancer cells.Thu, 15 Nov 2012 13:29:29 ESThttp://www.sciencedaily.com/releases/2012/11/121115132903.htmNewly discovered enzyme important in the spreading of cancerhttp://www.sciencedaily.com/releases/2012/11/121115132901.htm Enzyme hunters at UiO have discovered the function of an enzyme that is important in the spreading of cancer. Cancer researchers now hope to inhibit the enzyme.Thu, 15 Nov 2012 13:29:29 ESThttp://www.sciencedaily.com/releases/2012/11/121115132901.htmGenetics point to serious pregnancy complication, pre-eclampsiahttp://www.sciencedaily.com/releases/2012/11/121115132613.htm New research has revealed a genetic link in pregnant moms - and their male partners - to pre-eclampsia, a life-threatening complication during pregnancy.Thu, 15 Nov 2012 13:26:26 ESThttp://www.sciencedaily.com/releases/2012/11/121115132613.htmMolecular mechanisms underlying stem cell reprogramming decodedhttp://www.sciencedaily.com/releases/2012/11/121115132344.htm Thanks to some careful detective work, scientist better understand just how iPS cells form ? and why the Yamanaka process is inefficient, an important step to work out for regenerative medicine. The findings uncover cellular impediments to iPS cell development that, if overcome, could dramatically improve the efficiency and speed of iPS cell generation.Thu, 15 Nov 2012 13:23:23 ESThttp://www.sciencedaily.com/releases/2012/11/121115132344.htmSurprising genetic link between kidney defects and neurodevelopmental disorders in kidshttp://www.sciencedaily.com/releases/2012/11/121115132342.htm About 10 percent of kids born with kidney defects have large alterations in their genomes known to be linked with neurodevelopmental delay and mental illness, a new study has shown.Thu, 15 Nov 2012 13:23:23 ESThttp://www.sciencedaily.com/releases/2012/11/121115132342.htmEven moderate drinking in pregnancy can affect a child's IQhttp://www.sciencedaily.com/releases/2012/11/121114172833.htm Relatively small levels of exposure to alcohol while in the womb can influence a child's IQ, according to a new study using data from over 4,000 mothers and their children.Wed, 14 Nov 2012 17:28:28 ESThttp://www.sciencedaily.com/releases/2012/11/121114172833.htmGene nearly triples risk of Alzheimer's, international research team findshttp://www.sciencedaily.com/releases/2012/11/121114171710.htm A gene so powerful it nearly triples the risk of Alzheimer's disease has been discovered by an international team of researchers. It is the most potent genetic risk factor for Alzheimer's identified in the past 20 years.Wed, 14 Nov 2012 17:17:17 ESThttp://www.sciencedaily.com/releases/2012/11/121114171710.htmDiscovery could lead to faster diagnosis for some chronic fatigue syndrome caseshttp://www.sciencedaily.com/releases/2012/11/121114171708.htm For the first time, researchers have landed on a potential diagnostic method to identify at least a subset of patients with chronic fatigue syndrome - testing for antibodies linked to latent Epstein-Barr virus reactivation.Wed, 14 Nov 2012 17:17:17 ESThttp://www.sciencedaily.com/releases/2012/11/121114171708.htmResearch breakthrough could halt melanoma metastasis, study suggestshttp://www.sciencedaily.com/releases/2012/11/121114153227.htm In laboratory experiments, scientists have eliminated metastasis, the spread of cancer from the original tumor to other parts of the body, in melanoma by inhibiting a protein known as melanoma differentiation associated gene-9 (mda-9)/syntenin.Wed, 14 Nov 2012 15:32:32 ESThttp://www.sciencedaily.com/releases/2012/11/121114153227.htmPig genomes provide massive amount of genomic data for human healthhttp://www.sciencedaily.com/releases/2012/11/121114134512.htm Researchers provide a whole-genome sequence and analysis of number of pig breeds, including a miniature pig that serves a model for human medical studies and therapeutic drug testing.Wed, 14 Nov 2012 13:45:45 ESThttp://www.sciencedaily.com/releases/2012/11/121114134512.htmRare parasitic fungi could have anti-flammatory benefitshttp://www.sciencedaily.com/releases/2012/11/121114134054.htm Caterpillar fungi are rare parasites found on hibernating caterpillars in the mountains of Tibet. For centuries they have been highly prized as a traditional Chinese medicine - just a small amount can fetch hundreds of dollars.Wed, 14 Nov 2012 13:40:40 ESThttp://www.sciencedaily.com/releases/2012/11/121114134054.htmCancer therapy: Nanokey opens tumors to attackhttp://www.sciencedaily.com/releases/2012/11/121114113803.htm There are plenty of effective anticancer agents around. The problem is that, very often, they cannot gain access to all the cells in solid tumors. A new gene delivery vehicle may provide a way of making tracks to the heart of the target.Wed, 14 Nov 2012 11:38:38 ESThttp://www.sciencedaily.com/releases/2012/11/121114113803.htmHigh sperm DNA damage a leading cause of 'unexplained infertility', research findshttp://www.sciencedaily.com/releases/2012/11/121114113235.htm New research has uncovered the cause of infertility for 80 per cent of couples previously diagnosed with 'unexplained infertility': high sperm DNA damage.Wed, 14 Nov 2012 11:32:32 ESThttp://www.sciencedaily.com/releases/2012/11/121114113235.htmA risk gene for cannabis psychosishttp://www.sciencedaily.com/releases/2012/11/121114083928.htm The ability of cannabis to produce psychosis has long been an important public health concern. This concern is growing in importance as there is emerging data that cannabis exposure during adolescence may increase the risk of developing schizophrenia, a serious psychotic disorder. Further, with the advent of medical marijuana, a new group of people with uncertain psychosis risk may be exposed to cannabis.Wed, 14 Nov 2012 08:39:39 ESThttp://www.sciencedaily.com/releases/2012/11/121114083928.htmBacterial DNA sequence used to map an infection outbreakhttp://www.sciencedaily.com/releases/2012/11/121113214635.htm For the first time, researchers have used DNA sequencing to help bring an infectious disease outbreak in a hospital to a close. Researchers used advanced DNA sequencing technologies to confirm the presence of an ongoing outbreak of methicillin-resistant Staphylococcus aureus (MRSA) in a Special Care Baby Unit in real time. This assisted in stopping the outbreak earlier, saving possible harm to patients. This approach is much more accurate than current methods used to detect hospital outbreaks.Tue, 13 Nov 2012 21:46:46 ESThttp://www.sciencedaily.com/releases/2012/11/121113214635.htmGenetic variation may modify associations between low vitamin D levels and adverse health outcomeshttp://www.sciencedaily.com/releases/2012/11/121113161506.htm Findings from a study suggest that certain variations in vitamin D metabolism genes may modify the association of low serum 25-hydroxyvitamin D concentrations with health outcomes such as hip fracture, heart attack, cancer, and death.Tue, 13 Nov 2012 16:15:15 ESThttp://www.sciencedaily.com/releases/2012/11/121113161506.htmNew type of bacterial protection found within cells: Novel immune system response to infections discoveredhttp://www.sciencedaily.com/releases/2012/11/121113143656.htm Biologists have discovered that fats within cells store a class of proteins with potent antibacterial activity, revealing a previously unknown type of immune system response that targets and kills bacterial infections.Tue, 13 Nov 2012 14:36:36 ESThttp://www.sciencedaily.com/releases/2012/11/121113143656.htmGlutamate neurotransmission system may be involved with depression riskhttp://www.sciencedaily.com/releases/2012/11/121113134807.htm Researchers using a new approach to identifying genes associated with depression have found that variants in a group of genes involved in transmission of signals by the neurotransmitter glutamate appear to increase the risk of depression.Tue, 13 Nov 2012 13:48:48 ESThttp://www.sciencedaily.com/releases/2012/11/121113134807.htmTargeting downstream proteins in cancer-causing pathway shows promise in cell, animal modelhttp://www.sciencedaily.com/releases/2012/11/121113134230.htm The cancer-causing form of the gene Myc alters the metabolism of mitochondria, the cell?s powerhouse, making it dependent on the amino acid glutamine for survival. Depriving cells of glutamine selectively induces programmed cell death in cells overexpressing mutant Myc. Using Myc-active neuroblastoma cells, a team three priotein executors of the glutamine-starved cell, representing a downstream target at which to aim drugs. Roughly 25 percent of all neuroblastoma cases are associated with Myc-active cells.Tue, 13 Nov 2012 13:42:42 ESThttp://www.sciencedaily.com/releases/2012/11/121113134230.htmEven low-level radioactivity is damaging, scientists concludehttp://www.sciencedaily.com/releases/2012/11/121113134224.htm Even the very lowest levels of radiation are harmful to life, scientists have concluded, reporting the results of a wide-ranging analysis of 46 peer-reviewed studies published over the past 40 years. Variation in low-level, natural background radiation was found to have small, but highly statistically significant, negative effects on DNA as well as several measures of health.Tue, 13 Nov 2012 13:42:42 ESThttp://www.sciencedaily.com/releases/2012/11/121113134224.htmLoss of essential blood cell gene leads to anemiahttp://www.sciencedaily.com/releases/2012/11/121113122220.htm Scientists have discovered a new gene that regulates heme synthesis in red blood cell formation. Heme is the deep-red, iron-containing component of hemoglobin, the protein in red blood cells responsible for transporting oxygen in the blood. The findings promise to advance the biomedical community's understanding and treatment of human anemias and mitochondrial diseases, both known and unknown.Tue, 13 Nov 2012 12:22:22 ESThttp://www.sciencedaily.com/releases/2012/11/121113122220.htmWatching the developing brain, scientists glean clues on neurological disorderhttp://www.sciencedaily.com/releases/2012/11/121113122133.htm Researchers have tracked a gene's crucial role in orchestrating the placement of neurons in the developing brain. Their findings help unravel some of the mysteries of Joubert syndrome and other neurological disorders.Tue, 13 Nov 2012 12:21:21 ESThttp://www.sciencedaily.com/releases/2012/11/121113122133.htmSolving the mystery of aging: Longevity gene makes Hydra immortal and humans grow olderhttp://www.sciencedaily.com/releases/2012/11/121113091953.htm Why do we get older? When do we die and why? Is there a life without aging? For centuries, science has been fascinated by these questions. Now researchers have examined why the polyp Hydra is immortal -- and unexpectedly discovered a link to aging in humans.Tue, 13 Nov 2012 09:19:19 ESThttp://www.sciencedaily.com/releases/2012/11/121113091953.htmMen and women battle for ideal height: Evidence of an intralocus sexual conflict currently raging in human DNAhttp://www.sciencedaily.com/releases/2012/11/121113083536.htm A battle about the ideal height would appear to be raging in men's and women's genes. A researcher in Sweden has shown that this conflict is leading to a difference in reproductive success between men and women of varying height.Tue, 13 Nov 2012 08:35:35 ESThttp://www.sciencedaily.com/releases/2012/11/121113083536.htmCatch and release of rare cancer cells inspired by jellyfishhttp://www.sciencedaily.com/releases/2012/11/121112171314.htm A research team has developed a novel device that may one day have broad therapeutic and diagnostic uses in the detection and capture of rare cell types, such as cancer cells, fetal cells, viruses and bacteria.Mon, 12 Nov 2012 17:13:13 ESThttp://www.sciencedaily.com/releases/2012/11/121112171314.htmJellyfish-inspired device that captures cancer cells from blood samples could enable better patient monitoringhttp://www.sciencedaily.com/releases/2012/11/121112171312.htm Tumor cells circulating in a patient's bloodstream can yield a great deal of information on how a tumor is responding to treatment and what drugs might be more effective against it. But first, these rare cells have to be captured and isolated from the many other cells found in a blood sample. Scientists are now working on microfluidic devices that can isolate circulating tumor cells.Mon, 12 Nov 2012 17:13:13 ESThttp://www.sciencedaily.com/releases/2012/11/121112171312.htmNew cause of thyroid hormone deficiency discoveredhttp://www.sciencedaily.com/releases/2012/11/121112135615.htm Researchers have discovered a new cause for thyroid hormone deficiency, or hypothyroidism. The scientists identified a new hereditary form of hypothyroidism that is more prevalent in males than in females. This sex bias shone a light on where to look for the underlying cause.Mon, 12 Nov 2012 13:56:56 ESThttp://www.sciencedaily.com/releases/2012/11/121112135615.htmGenetic link between pancreatitis and alcohol consumptionhttp://www.sciencedaily.com/releases/2012/11/121112135520.htm A new study reveals a genetic link between chronic pancreatitis and alcohol consumption. Researchers found a genetic variant on chromosome X near the claudin-2 gene (CLDN2) that predicts which men who are heavy drinkers are at high risk of developing chronic pancreatitis.Mon, 12 Nov 2012 13:55:55 ESThttp://www.sciencedaily.com/releases/2012/11/121112135520.htmHumans are slowly but surely losing intellectual and emotional abilities, article suggestshttp://www.sciencedaily.com/releases/2012/11/121112135516.htm Human intelligence and behavior require optimal functioning of a large number of genes, which requires enormous evolutionary pressures to maintain. A provocative theory suggests that we are losing our intellectual and emotional capabilities because the intricate web of genes endowing us with our brain power is particularly susceptible to mutations and that these mutations are not being selected against in our modern society.Mon, 12 Nov 2012 13:55:55 ESThttp://www.sciencedaily.com/releases/2012/11/121112135516.htmHow chronic inflammation can cause cancerhttp://www.sciencedaily.com/releases/2012/11/121112135512.htm A new study has found that interleukin-15 (IL-15) alone can cause large granular lymphocytic (LGL) leukemia, a rare and usually fatal form of cancer. The researchers developed a treatment for the leukemia that showed no discernible side effects in an animal model. The study shows that IL-15 is also overexpressed in patients with LGL leukemia and that it causes similar cellular changes, suggesting that the treatment should also benefit people with the malignancy.Mon, 12 Nov 2012 13:55:55 ESThttp://www.sciencedaily.com/releases/2012/11/121112135512.htmList of diseases spread by deer tick grows, including malaria-like problems and potentially fatal encephalitishttp://www.sciencedaily.com/releases/2012/11/121112135510.htm An emerging tick-borne disease that causes symptoms similar to malaria is expanding its range in areas of the northeast where it has become well-established, according to new research.Mon, 12 Nov 2012 13:55:55 ESThttp://www.sciencedaily.com/releases/2012/11/121112135510.htmParkinson's disease: Compensation in the brain could lead to new treatmenthttp://www.sciencedaily.com/releases/2012/11/121112135404.htm New evidence indicates that Parkinson's disease is preceded by a period during which healthy regions of the brain take over the functions of damaged ones.Mon, 12 Nov 2012 13:54:54 ESThttp://www.sciencedaily.com/releases/2012/11/121112135404.htm

Source: http://www.sciencedaily.com/rss/health_medicine/genes.xml

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Monday, November 19, 2012

Bucs beat Panthers for 4th straight win

By STEVE REED

AP Sports Writer

Associated Press Sports

updated 5:37 p.m. ET Nov. 18, 2012

CHARLOTTE, N.C. (AP) - The Tampa Bay Buccaneers are starting to look and talk like a legitimate playoff contender.

The Bucs had to work a little extra to keep their playoff surge alive Sunday. Josh Freeman threw a 15-yard touchdown pass to Dallas Clark in overtime to cap the Buccaneers' 27-21 comeback win over the Carolina Panthers.

It was Freeman's third touchdown pass of the game for the Bucs (6-4), who have won five of their last six to pull into playoff contention.

But rather than celebrating their dramatic win, Clark talked afterward about learning from it.

"We learned a lesson today that we can't just show up and win a game," Clark said. "I hope guys will get it. We're lucky it's not a loss. I hope we go back and look at the film and say, `Hey we didn't play well.' Sure, we played well enough to make some plays to win at the end, but to get where we want to go, that's not good enough football."

Meanwhile, the Panthers (2-8) would love to have a win any way they can get it.

Carolina has lost seven of its last eight. The Panthers held a fourth-quarter lead in five of their last six defeats before fading in the final seconds.

"It's been the story of our season," said Cam Newton, who threw for 252 yards and a touchdown to fall to 8-18 as an NFL starter.

When asked where this loss ranked among this season's meltdowns, Newton snapped, "I'm not answering no more questions about where this one ranks."

Carolina appeared to have the game in hand when Newton connected on a 29-yard touchdown strike to Brandon LaFell to go up 21-10 with six minutes left in regulation.

But after a 40-yard field goal by Connor Barth, the Panthers' offense couldn't put the game away and had to punt.

Freeman quickly led the Bucs 80 yards on seven plays in 50 seconds, despite not having any timeouts. Along the way, the Bucs benefited from a personal foul penalty on linebacker Thomas Davis for hitting a defenseless receiver.

Freeman finished the drive with a perfectly thrown 24-yard touchdown pass to Vincent Jackson between three defenders with 12 seconds left. He went back to Jackson for a 2-point conversion on a slant route to send it into overtime.

In overtime, the Bucs won the coin toss and moved quickly down the field with Freeman finding an open Clark on a wheel route along the left sideline for the winner.

"You've got to love it when the linebacker swears as you're heading up field," Clark said with a laugh.

Freeman said it was a play the Bucs worked on all week and he's glad that was the call.

"When we got to overtime we stepped into the huddle and everybody was ready to go and we started talking like, `Hey let's just execute one play at a time and do our jobs and try to get out of this thing with a touchdown,"' Freeman said.

The Bucs came in as one of the hottest teams in the league, having scored an average of 35.6 points per game during the past five games. Freeman had thrown 13 touchdown passes and only one interception in those games.

But after Tampa Bay jumped to a 10-0 lead the Panthers' defense shut them down for most of the remainder of the three quarters, forcing three turnovers. A 74-yard interception return for a touchdown by Captain Munnerlyn and a key fumble by rookie Doug Martin on a fourth-and-goal at the 1-yard line loomed large.

Trailing 14-10, the Bucs appeared ready to take the lead after driving 15 plays to the Carolina 1.

But on fourth down, coach Greg Schiano went for the touchdown instead of the field goal and linebacker Davis plowed into Martin, forcing the ball out near the goal line. Fellow linebacker Luke Kuechly, the team's first-round draft pick, recovered in the end zone for a touchback.

Officials reviewed the play to see if Martin got in, but the call stood.

The Panthers seized the momentum when Newton led the team 80 yards for a score to build a 21-10 lead.

But once again, the Panthers couldn't finish.

Second-year coach Ron Rivera, whose seat only grew hotter after the loss, said the game was all about missed opportunities. Rivera said the loss "is right up there at the top" in terms of toughest ones to swallow.

"This is about as bad as it gets," he said. "The bad part is when you have opportunities to close someone out with a four-minute offense, but you can't take negative plays. That's a tough one."

NOTES: Freeman has now thrown 16 touchdown passes in the last six games. ... Wide receiver Steve Smith injured his hand and defensive end Charles Johnson his head during the game, but both returned. ... Martin had 138 yards rushing for the Bucs. ... Carolina had 97 yards rushing after being held to 10 in the last meeting with the Bucs in the season opener.

---

Online: http://pro32.ap.org/poll and http://twitter.com/AP-NFL

? 2012 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


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Schaub rallies Texans with 5 TDs

Matt Schaub and Andre Johnson hooked up on a 48-yard touchdown strike with 2:01 left in overtime, and the Texans pulled out a 43-37 win over the Jaguars on Sunday.

Ravens rough up shorthanded Steelers

??Jacoby Jones had a 63-yard punt return for a touchdown and Justin Tucker made two of his three field-goal attempts to give the Baltimore Ravens a 13-10 victory over the Pittsburgh Steelers in their AFC North showdown Sunday night.

Source: http://nbcsports.msnbc.com/id/49877191/ns/sports-nfl/

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Wednesday, November 14, 2012

Scandal widens; US general's emails 'flirtatious'

Jill Kelley leaves her home Tuesday, Nov 13, 2012 in Tampa, Fla. Kelley is identified as the woman who allegedly received harassing emails from Gen. David Petraeus' paramour, Paula Broadwell. She serves as an unpaid social liaison to MacDill Air Force Base in Tampa, where the military's Central Command and Special Operations Command are located. (AP Photo/Chris O'Meara)

Jill Kelley leaves her home Tuesday, Nov 13, 2012 in Tampa, Fla. Kelley is identified as the woman who allegedly received harassing emails from Gen. David Petraeus' paramour, Paula Broadwell. She serves as an unpaid social liaison to MacDill Air Force Base in Tampa, where the military's Central Command and Special Operations Command are located. (AP Photo/Chris O'Meara)

Paula Broadwell holds a drink in the kitchen of her brother's house in Washington, Tuesday, Nov. 13, 2012. Broadwell is CIA Director David Petraeus' biographer, with whom he had an affair that led to his abrupt resignation last Friday. It was Broadwell's threatening emails to Jill Kelley, a Florida woman who is a Petraeus family friend, that led to the FBI's discovery of communications between Broadwell and Petraeus indicating they were having an affair. (AP Photo/Cliff Owen)

FILE POOL - In this July 9, 2011 file photo, USMC Gen. John Allen, left, and Army Gen. David Petraeus, top U.S. commander in Afghanistan and incoming CIA Director, greet former CIA Director and new U.S. Defense Secretary Leon Panetta, right, as he lands in Kabul, Afghanistan, Saturday, July 9, 2011. (AP Photo/Paul J. Richards, Pool)

Jill Kelley leaves her home Monday, Nov 12, 2012 in Tampa, Fla. Kelley is identified as the woman who allegedly received harassing emails from Gen. David Petraeus' paramour, Paula Broadwell. She serves as an unpaid social liaison to MacDill Air Force Base in Tampa, where the military's Central Command and Special Operations Command are located.

FILE -- In an April 28, 2011 file photo Marine Corps Lt. Gen. John Allen, speaks in the East Room of the White House in Washington. The sex scandal that led to CIA Director David Petraeus' downfall widened Tuesday with word the top U.S. commander in Afghanistan is under investigation for thousands of alleged "inappropriate communications" with another woman involved in the case. (AP Photo/Charles Dharapak/file)

(AP) ? The sex scandal that felled CIA Director David Petraeus widened Tuesday to ensnare the top U.S. commander in Afghanistan, Gen. John Allen, in a suddenly public drama involving a Tampa socialite, a jealous rival, a twin sister in a messy custody dispute and flirty emails.

The improbable story ? by turns tragic and silly ? could have major consequences, unfolding at a critical time in the Afghan war effort and just as President Barack Obama was hoping for a smooth transition in his national security team.

Obama put a hold on the nomination of Afghan war chief Allen to become the next commander of U.S. European Command as well as the NATO supreme allied commander in Europe after investigators uncovered 20,000-plus pages of documents and emails that involved Allen and Tampa socialite Jill Kelley. Some of the material was characterized as "flirtatious."

Allen, 58, has insisted he'd done nothing wrong and worked to save his imperiled career.

Gen. Martin Dempsey, chairman of the Joint Chiefs of Staff, has recommended to Defense Secretary Leon Panetta that he keep Allen in his post as commander in Afghanistan, Dempsey's spokesman, Col. David Lapan, said Tuesday.

Dempsey called Allen from Australia, where he was to attend meetings with Panetta, Secretary of State Hillary Rodham Clinton and their Australian counterparts. Allen told Dempsey that he had not committed any wrongdoing, Lapan said

Kelley, 37, who had worked herself into the center of the military social scene in Florida without having any official role, emerged as a central figure in the still-unfolding story that has embroiled two of the nation's most influential and respected military leaders.

Known as a close friend of retired Gen. Petraeus, Kelley triggered the FBI investigation that led to his downfall as CIA director when she complained about getting anonymous, harassing emails. They turned out to have been written by Petraeus' mistress, Paula Broadwell, who apparently was jealous of the attention the general paid to Kelley. Petraeus acknowledged the affair and resigned Friday.

In the course of looking into that situation, federal investigators came across what a Pentagon official called "inappropriate communications" between Allen and Kelley, both of them married.

According to one senior U.S. official, the emails between Allen and Kelley were not sexually explicit or seductive but included pet names such as "sweetheart" or "dear." The official said that while much of the communication ? including some from Allen to Kelley ? is relatively innocuous, some could be construed as unprofessional and would cause a reasonable person to take notice.

That official, as well as others who described the investigation, requested anonymity on grounds that they were not authorized to discuss the situation publicly.

The FBI decided to turn over the Allen information to the military once the bureau recognized it contained no evidence of a federal crime, according to a federal law enforcement official, who was not authorized to discuss the matter on the record and demanded anonymity. Adultery, however, is a crime under the Uniform Code of Military Justice.

A senior defense official said that the FBI first notified the Pentagon of the Allen matter at 4:15 p.m. EST on Sunday. The Pentagon's top lawyer, Jeh Johnson, then called Panetta's chief of staff, Jeremy Bash, about 5 p.m. as Bash and Panetta were flying to Honolulu aboard a military jet to begin a weeklong Asia trip. Bash then informed Panetta.

Allen was not suspended from his military position, even though his nomination for promotion is on hold. The White House will soon be deciding how many troops will remain in Afghanistan ? and for what purposes ? after the U.S.-led combat operation ends in 2014. Allen has provided his recommendations to the White House and is key to those discussions.

Still more subplots in the story emerged Tuesday with news that both Allen and Petraeus wrote letters last September on behalf of Jill Kelley's twin sister, Natalie Khawam, in a messy custody dispute. In 2011, a judge had denied Khawam custody of her 3-year-old son, saying she "appears to lack any appreciation or respect for the importance of honesty and integrity in her interactions with her family, employers and others with whom she comes in contact."

Allen, in his letter, wrote of Khawam's "maturity, integrity and steadfast commitment to raising her child." Petraeus wrote that he'd been host for the Kelley family and Khawam and her son for Christmas dinner, and he described a loving relationship with her son. That also indicated how close the Petraeus and Kelley families had been.

Kelley served as a sort of social ambassador for U.S. Central Command in Tampa, hosting parties for Petraeus when he was commander there from 2008-10.

The friendship with the Petraeus began when they arrived in Tampa, and the Kelleys threw a welcome party at their home, a short distance from Central Command headquarters, introducing the new chief and his wife, Holly, to Tampa's elite, according to staffers who served with Petraeus.

Such friendships among senior military commanders and prominent local community leaders are common at any base, a relationship where the officers invite local people to exclusive military events and functions, and the invitees respond by providing private funding to support troops with everything from morale-boosting "Welcome Home" parades to assistance for injured combat veterans.

Petraeus aides say Jill Kelley took it to another level, winning the title of "honorary ambassador" from the countries involved in the Afghan war for her extensive entertaining at her home on behalf of the command, throwing parties that raised her social status in Tampa through the reflected glow of the four-star general in attendance.

Petraeus even honored Kelley and her husband with an award given to them in a special ceremony at the Pentagon just before he left the military for his post at the CIA, an aide said, speaking on condition of anonymity because he was not authorized to comment on the matter publicly.

White House spokesman Jay Carney, employing understatement, was asked about the revelations involving Allen and said Obama "wouldn't call it welcome" news. Carney described Obama as "surprised" by the earlier news about Petraeus.

As he prepares for a second term, the president has hoped to run a methodical transition process, with the goal of keeping many Cabinet members and other high-ranking officials in their posts until successors are confirmed, or at least nominated. Petraeus' resignation has disrupted those plans, leaving Obama with an immediate vacancy to fill and raising questions about how much other immediate shake-up the national security team can handle.

National Security Council spokesman Tommy Vietor said Obama put Allen's nomination on hold at the request of Panetta. The general succeeded Petraeus as the top American commander in Afghanistan in July 2011 and has been working with Panetta on how best to pace the withdrawal of U.S. troops.

Vietor said in a written statement that Obama "remains focused on fully supporting our extraordinary troops and coalition partners in Afghanistan, who Gen. Allen continues to lead as he has so ably done for over a year."

The unfolding story caused a commotion on Capitol Hill as well, as lawmakers complained that they should have been told about the investigation earlier.

Rep. Peter King, R-N.Y., chairman of the House Homeland Security Committee, called the latest revelations "a Greek tragedy."

Acting CIA Director Michael Morell met with Senate Intelligence Committee Chairwoman Dianne Feinstein, D-Calif., and ranking Republican Saxby Chambliss of Georgia on Tuesday, to explain the CIA's understanding of events that led Petraeus to resign. That session came ahead of meetings with the leaders of the House Intelligence Committee on Wednesday, according to congressional aides.

The chairman and top Republican on the Senate Armed Services Committee said their panel would go ahead with Thursday's scheduled confirmation hearing on the nomination of Marine Corps Gen. Joseph Dunford, who is to replace Allen as commander of U.S. and NATO forces in Afghanistan, if Allen is indeed promoted.

Even though Petraeus has stepped down, Sen. Carl Levin, chairman of the Armed Services Committee, said the retired general should testify about the Sept. 11 attack on the U.S. Consulate in Benghazi, Libya, "if he has relevant information." Sen. Susan Collins, R-Maine, said it was "absolutely imperative" that Petraeus testify, since he was CIA director during the attack and visited Libya afterward.

Asked by reporters if there was a national security breach with the Petraeus affair, Feinstein said: "We're going to hold an inquiry. We're going to look at things. I have no evidence that there was at this time." She said she expected Petraeus to testify ? "if not this week, then another week. That's for sure."

Feinstein said did not believe that either Allen or Petraeus would release classified information.

The FBI looked into whether a separate set of emails between Petraeus and Broadwell might involve any security breach and concluded it did not.

The FBI searched Broadwell's home in Charlotte, N.C., Monday night, with her consent, according to a federal law enforcement official, who requested anonymity because the official was not authorized to speak on the record about the investigation.

The official said the FBI just wanted to make sure there were no classified documents out of government custody.

___

Associated Press writers Lolita Baldor, Pete Yost, Kimberly Dozier, Adam Goldman, Jack Gillum, Larry Margasak, Julie Pace, Donna Cassata and Robert Burns contributed to this report.

___

Follow Nancy Benac on Twitter: http://www.twitter.com/nbenac

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/89ae8247abe8493fae24405546e9a1aa/Article_2012-11-13-US-Generals-Scandal/id-cb56e86aad8c4d31a1039c9219bdf369

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Friday, November 9, 2012

Time Warner posts higher third-quarter profit

(Reuters) - Time Warner Inc posted a higher third-quarter profit on Wednesday as growth in its cable networks offset declines in its film and TV entertainment business.

Net income for the company, which owns a host of cable networks, premium TV service HBO, magazines and a movie studio, rose to $838 million, or 86 cents a share, from $822 million, or 78 cents a share, a year earlier.

The results beat the analysts' average estimate of 82 cents per share compiled by Thomson Reuters I/B/E/S.

Revenue fell 3 percent to $6.84 billion. Analysts were expecting $6.89 billion.

The company affirmed its full-year outlook, which calls for earnings growth, excluding special items, at a low double-digit percentage rate from $2.89 a share last year. Analysts have forecast $3.20.

A day earlier, Time Warner peer Discovery Communications Inc cut its revenue outlook for the year.

Also on Tuesday, media company News Corp reported strength in its cable unit, lifted by growth at regional sports networks, the FX cable network and Fox news channel.

Time Warner logged a 4 percent revenue increase at its networks division, which includes TNT, TBS, HBO and CNN. But the growth stemmed from subscription revenue from cable operators, while advertising in the segment fell 1 percent.

Revenue at the film and TV entertainment unit dropped 12 percent, or $400 million, from a year earlier, when the company released "Harry Potter and the Deathly Hallows: Part 2," the final installment in the fantasy series.

Revenue in the publishing unit, whose titles include Time and Sports Illustrated, declined 6 percent, or $51 million, as advertising sales and subscription revenue fell.

(Reporting by Liana B. Baker; Editing by Gerald E. McCormick and Lisa Von Ahn)

Source: http://news.yahoo.com/time-warner-posts-higher-third-quarter-profit-121243804--finance.html

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Thursday, November 8, 2012

#39Hurry Up Christmas Special!#39 Downton Abbey Ends As ...

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On-schedule Mick#39s no hurry Potter HE was announced as Wests Tigers coach less than a fortnight ago, yet after taking charge of his first training session with his new club, Mick Potter insisted the pre-season was #39#39on schedule#39#39.Discount

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M83#39s Hurry Up, We#39re Dreaming Gets Deluxe Edition M83 #39s biggest album continues to grow. This time, Hurry Up, We#39re Dreaming will be offered as a deluxe version that includes remixes from Trentemller, Mylo, Team Ghost aka former M83 member Nicolas Fromageau, White Sea aka M83 collaborator Morgan Kibby, and more. That#39s available now as a 3xCD set or digital release. Hurry Up, We#39re Dreaming Deluxe Edition disc 3 01 Midnight City Eric Clicking Here

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The Hurry Cane Supports Delaware in Efforts to Increase Walking Among Residents In an effort to fight against rising rates of childhood obesity, the state of Delaware has announced plans to encourage fitness by developing biking and walking trails. As a company that aims to improve mobility, The Hurry Cane applauds these actions.New York, New York PRWEB November 06, 2012 Although childhood obesity continues to raise concern among citizens across the United States, health http://www.viettribe.com/blog/6714/printable-80th-birthday-invitations/

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Breakfast links Should Cowboys hurry up Methinks, methinks you#39d like some links. New York Giants Mike Garafolo looks at what#39s wrong with the Giants#39 passing game right now, and lays a pretty fair share of the blame at the feet of two-time Super Bowl MVP quarterback Eli Manning. The Giants are taking their role in this area#39s recovery from Hurricane Sandy quite seriously. The team is donating $500,000 to relief efforts, and players Hannah

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Govt told to hurry up on Cook Strait decision Business leaders are urging the Government to decide future transport arrangements for Cook Strait.http://phpfox.viewmix.tv/index.php?do=/blog/2210/printable-fake-money-for-free/

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Driskel Talks About the Use of the quotHurry Upquot by the Gator Offense Gainesville, FL?The Florida Gators are getting set for a visit from Louisiana Lafayette and fans are wondering if they will go to a quothurry upquot offense again.To

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Source: http://www.bucksandspurs.com/blog/39hurry-up-christmas-special39-downton-abbey-ends-as-excitement-for-festive-special-begins

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What You Need to Have in Your Social Media Toolbox | Best Legal ...

Social media is shaping the way marketing and communication are conducted online. For law firms and solo attorneys whose Internet presence is limited to a website, getting started with online social networking may seem a bit complicated. Social media marketing is far more sophisticated than the Search Engine Optimization strategies of yesteryear, and legal professionals are urged to put together a social media toolbox with readily-available resources.

Since social media marketing is a burgeoning discipline, the number of social media tools is staggering. The tools chosen by a law firm will largely depend on the specific fields of practice. A Las Vegas personal injury lawyer working mostly by himself will probably not need a group messaging tool, but he may need to monitor the social media sphere with a service that provides daily alerts.

The following social media marketing tools are ideal for legal professionals:

Facebook

A couple of years ago, some staid law firms questioned the value of establishing a Facebook profile. They mostly feared that the world?s most powerful online social network would turn into a garish MySpace-like experience. Now that 1 billion members have made the network their favorite Internet platform, the value Facebook Timeline has increased exponentially. If there is a single network that legal professionals should be in, it might as well be Facebook.

Customer service platforms

Companies like Groupon, Hertz and Zappos keep entire customer service platforms on social networks. Law firms with multiple partners and associates can centralize their client service operations with solutions like Conversocial, a software platform that turns Facebook and Twitter profiles into customer service centers.

Research and alerts

Online social networking has paved the way for a real-time Internet paradigm. This means that social media netizens thrive on up-to-date information. Legal professionals can stay abreast of events shaping the social media sphere with a service like Social Mention, which provides insight on active trends, brands and topics.

Business Cards

LinkedIn, the premier business social network, can be described as a massive virtual business card exchange. Attorneys who use iPhones can now turn their smartphones into business cards scanners with apps like CardMunch, which automatically connects to LinkedIn to retrieve information and business connections.

Group Communications

Collaborative work is the cornerstone of any law firm. Group messaging tools with social media features like Campfire are ideal platforms for legal professionals to work together. These applications can be used internally or from outside the office.

About

Vanessa Setteducato has exercised her legal marketing skills with a nine to five that includes search engine optimization, social media and managing a network of blogs created by LexisNexis to promote community within the world of law firm marketing.

Related posts:

  1. Ways to Appear More Human on Social Media
  2. Social Media Tools Not Best Choice for Legal Marketing
  3. How to Use Social Media Effectively

Source: http://www.bestlegalmarketing.com/social-media/what-you-need-to-have-in-your-social-media-toolbox/

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Friday, November 2, 2012

AT&T and T-Mobile to share networks in hurricane aftermath

Android Central

AT&T and T-Mobile have struck up an agreement to share their networks in the New York and New Jersey area. They will enable roaming to mutual customers to share network capacity, so that those having trouble getting a cell signal may have a better chance.

The carriers said that customers can carry on using their devices as per normal, with voice and data traffic going over whichever network is most operational in their area. Since both carriers are GSM-based, sharing should be seamless for users.

Hurricane Sandy has caused a widespread power blackout in cities on the East Coast, and carriers have suffered infrastructure damage in its wake. In addition, it led to Google's last-minute cancelation of its anticipated Monday event.

Today's full press release can be found after the break.

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Source: http://feedproxy.google.com/~r/androidcentral/~3/IeL_YKO0xZk/story01.htm

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Explore the Best Internet Marketing Techniques | the e of Marketing

Whether you call it e-marketing, online marketing or webvertising, the fact remains the same: Internet marketing is a rapidly growing field, since more and more people across the globe are gaining access to the Internet day by day. It is a field that brings together both the technical and the creative aspects of the Internet, and the result is a nicely laid-out marketing plan for a particular product or service.

Internet marketing

Image Credit: David Erickson

There are many types of Internet marketing techniques, and even more types of Internet marketing companies are in operation. We are going to discuss a few such techniques, as listed in the latest presentation:

Banner placement: Probably the simplest and the most trivial method of Internet marketing is banner placement. In this technique, you place small banners of the product or services as advertisements on various other websites for people to have a look. This attracts traffic to the product?s own website. The key here is to design such an attractive banner or advertisement that the viewer is compelled to check it out.

Search Engine Marketing: To put it simply, these are the ads that you see when you search a word, a product or a service on the search engine (like Google). This is a more technical aspect of marketing that places ads that are related to the words entered by that person in the search engine. This method focuses on increasing the visibility of a web page thereby promoting a product or service.

Search Engine Optimisation: Unlike the previous method, this one is an unpaid technique that improves the presence of a website on a search engine result page and/or improves the rank of the website in the search engine results. The idea behind this is to increase the number of times a particular word or phrase appears in the content of the website so that whenever the search engines try to find a particular word related to a product, your website is among those which contain the words the maximum number of times (but within a reasonable limit, of course). SEO goes a lot deeper than that, but in layman terms, the purpose of SEO is to optimise on-page and off-page content linked to your site in such a way that search engines prefer it over other sites due to higher relevance.

Social Media Marketing: This relatively new technique focuses on promoting the products and services on social media websites like Facebook, LinkedIn and Twitter. It is a known fact that every day more and more people open an account on these websites, and all these members of social networking websites are potential customers for various products. The idea behind this form of Internet marketing is to understand the likes and dislikes of the individuals on these websites and present them with ads related to their preferences.

Email Marketing: This, again, is a trivial form of marketing where emails promoting a product or advertising a service are sent to thousands of individuals at a time. This is more like a hit-and-trial method, but through this technique, one can promote his product or services to thousands of people across the globe, or any particular region for that matter, in a very short time.

Internet marketing is not limited to these methods, and other techniques include affiliate marketing, Video Marketing, referral marketing etc. If you are thinking about starting your own Internet marketing company, don?t forget to check out Spoton franchise UK?s latest offering called ?Internet marketing franchise in a box.?

About the Author:
Mike is a Sweden-based tech journalist who covers topics like Web 2.0, web design, and Search Engine Optimization. He also writes on freelance basis for
Spoton franchise UK.

Related posts:

  1. Internet Marketing: How To Get It Right
  2. Tips to Boost Online Marketing
  3. Tips to improve your online marketing strategy
  4. Technology Enhancing Modern Marketing
  5. The Google / Microsoft war.

Source: http://www.emarketingblog.co.za/2012/10/explore-the-best-internet-marketing-techniques/

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